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Laboratory Technician III/Research Assistant I/Research Assistant II

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Please see Special Instructions for more details.

This position is funded by a grant. Continuation is based upon available funds. Employment in this position is contingent upon consent to and successful completion of a pre-employment background check, which may include a criminal background check, reference checks, verification of work history, and verification of any required academic credentials, licenses, and/or certifications, with results acceptable to Dartmouth College. A criminal conviction will not automatically disqualify an applicant from employment. Background check information will be used in a confidential, non-discriminatory manner consistent with state and federal law.

Position Details

Position Information

Position Title Laboratory Technician III/Research Assistant I/Research Assistant II
Department Molecular and Systems Biology
Position Number 1125687
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Position Purpose

Laboratory Technician III:
To assist the principal investigator, postdoctoral associate, and graduate students in research studying the function of the Adenomatous polyposis coli (APC) tumor suppressor and beta-catenin oncogene in the evolutionarily conserved Wnt signal transduction pathway. Wnt signaling directs embryonic development and regulates stem cell biology in adults. Deregulation of Wnt signaling underlies the development of nearly all colon cancers, and also drives several other types of cancer. Thus key components of the Wnt signaling pathway have emerged as promising targets for the treatment of several types of cancer. We are investigating the function of APC, beta-catenin, and several therapeutic targets in Wnt signaling in both a fruit fly Drosophila model and in cultured colon cancer cells. Our research is at the intersection between genetics, cell, developmental, and cancer biology.

Research Assistant I:
To set up and conduct a variety of laboratory tests and experiments in support of research studies directed at studying the Wnt signal transduction pathway by applying established methods, procedures, and techniques. Wnt signaling directs embryonic development and regulates stem cell biology in adults. Deregulation of Wnt signaling underlies the development of nearly all colon cancers, and also drives several other types of cancer. Thus key components of the Wnt signaling pathway have emerged as promising targets for the treatment of several types of cancer. We are investigating the function of several therapeutic targets in Wnt signaling in both a fruit fly Drosophila model and in cultured colon cancer cells. Our research is at the intersection between genetics, cell, developmental, and cancer biology.

Research Assistant II:
To independently conduct experiments as defined in the research plan and to serve on a research team involved in the investigation of the Adenomatous polyposis coli (APC) tumor suppressor and beta-catenin oncogene in the evolutionarily conserved Wnt signal transduction pathway. Wnt signaling directs embryonic development and regulates stem cell biology in adults. Deregulation of Wnt signaling underlies the development of nearly all colon cancers, and also drives several other types of cancer. Thus key components of the Wnt signaling pathway have emerged as promising targets for the treatment of several types of cancer. We are investigating the function of APC, beta-catenin, and several therapeutic targets in Wnt signaling in both a fruit fly Drosophila model and in cultured colon cancer cells. Our research is at the intersection between genetics, cell, developmental, and cancer biology.

Skills & Knowledge

Laboratory Technician III

  • Competence in several laboratory methods, procedures and techniques as well as the equipment and instruments.
  • Ability to work independently with good judgment and good organizational and time management skills.
  • Willingness to work with hazardous chemicals.
  • Knowledge of computers and software applications.

Research Assistant I

  • Competence in several laboratory methods, procedures and techniques as well as the equipment and instruments.
  • Ability to work independently and apply critical thinking and sound judgment.
  • Good organizational and time management skills.
  • Willingness to work with/be exposed to hazardous materials such as hazardous chemicals.
  • Knowledge of computers and software applications.
  • Knowledge of standard computer software packages for data analysis and presentation, and on-line literature search engines.

Research Assistant II

  • Highly competent in several laboratory methods, procedures and techniques as well as the equipment and instruments.
  • Ability to work independently and apply critical thinking and sound judgment.
  • Ability to manage laboratory inventory and records.
  • Good organizational and time management skills.
  • Editorial skills for preparation of reports.
  • Willingness to work with/be exposed to hazardous materials such as radioactive materials, infectious materials, and/or hazardous chemicals.
  • Knowledge of computers and software applications.
  • Knowledge of standard computer software packages for data analysis and presentation, and on-line literature search engines. independently, with good work organization and time management skills, procedures and techniques and the equipment/instruments associated with them: management skills, skilled hands, and good judgment.
Minimum Experience

Laboratory Technician III

  • One year of relevant laboratory or science experience.

Research Assistant I

  • Two years of relevant laboratory/ research experience.

Research Assistant II

  • Three years of relevant laboratory/ research experience.
Minimum Education

Laboratory Technician III

  • Associate’s degree with a major in biology, chemistry, or biochemistry or the equivalent.
  • Bachelor’s degree with a major in biology, chemistry, or biochemistry.

Research Assistant I

  • Bachelor’s degree with a major in one of the Biological Sciences or the equivalent.

Research Assistant II

  • Bachelor’s degree with a major in one of the Biological Sciences or the equivalent.
SEIU Level Not an SEIU Position
FLSA Non-Exempt
Employment Category Regular Full Time
Department Contact for Cover Letter Cheryl Bush
Equal Opportunity Employer

Dartmouth College is an equal opportunity/affirmative action employer with a strong commitment to diversity and inclusion. We prohibit discrimination on the basis of race, color, religion, sex, age, national origin, sexual orientation, gender identity or expression, disability, veteran status, marital status, or any other legally protected status. Applications by members of all underrepresented groups are encouraged.

Special Instructions to Applicants

This position is funded by a grant. Continuation is based upon available funds.

Employment in this position is contingent upon consent to and successful completion of a pre-employment background check, which may include a criminal background check, reference checks, verification of work history, and verification of any required academic credentials, licenses, and/or certifications, with results acceptable to Dartmouth College. A criminal conviction will not automatically disqualify an applicant from employment. Background check information will be used in a confidential, non-discriminatory manner consistent with state and federal law.

Key Accountabilities

Key Accountabilities

Laboratory Technician III
Experiments

  • Conducts specified laboratory experiments/tests, utilizing a range of established methods, procedures, and techniques in molecular biology, biochemistry and confocal microsciopy.
  • Accomplishes necessary preparations to include equipment and instrumentation set-up, specimen preparation, etc.
  • Observes experiments/tests while in progress; records observations; trouble shoots as necessary.
  • Reconciles results that are disparate from anticipated findings; re-runs techniques as necessary.
  • Notifies principal investigator of problems associated with experiments, measurements, or analyses and suggests changes to methods, procedures, or techniques as appropriate.
  • Maintains laboratory notebook recording tasks performed.
  • Adheres to laboratory safety requirements including general and chemical/hazardous waste safety disposal methods

Records

  • Collects and analyzes data resulting from experimentation/testing and presents findings to Principal Investigator.
  • Prepares appropriate and understandable representations of data such as graphs, charts, tables, statistical summaries, etc.
  • Contributes to the preparation of scientific manuscripts by, preparing graphs, tables, and charts, etc.
  • Conducts literature searches to develop insights into the significance of experimental results and to acquire information on new or improved methods, procedures and techniques.

Laboratory

  • Helps to maintain lab stocks/reagents.
  • Orders laboratory supplies as needed.
  • Monitors laboratory equipment and instrument performance; obtains maintenance and repair as necessary.
  • Maintains computerized records associated with laboratory activities.
  • Instructs others in laboratory methods, procedures, and techniques and provides technical guidance and direction as required.

Miscellaneous

  • Communicates respectfully with a diverse community.

Research Assistant I
Experiments

  • Conducts experiments by applying established methods and procedures.
  • Sets up and assists with research protocols and experiments under the general guidance of the principal investigators and other senior investigators in the laboratory; may have primary responsibility for independently setting up, performing and trouble shooting less complex experiments.
  • Observes experimental results in progress and maintains written records of activities and observations; applies past experience and precedents to identify and troubleshoot problems.
  • Anticipates unexpected findings and assists in trouble-shoots techniques.
  • Reconciles results that are disparate from anticipated findings; re-runs techniques as necessary.
  • Reports experimental results to the principal investigator and other senior laboratory personnel and assists in their analysis
  • Collaborates with the Principal Investigator in investigating and developing modifications to techniques and documents all new techniques developed in the laboratory.
  • Adheres to laboratory safety requirements including general and chemical/hazardous waste safety disposal methods.

Records

  • Collects and analyzes data resulting from experimentation/testing.
  • Summarizes results and prepares progress reports for oral presentation at laboratory meetings.
  • Prepares appropriate and understandable representations of data such as graphs, charts, tables, statistical summaries, etc.
  • Contributes to the preparation of scientific manuscripts by drafting portions of the text, preparing graphs, tables, and charts, etc.
  • Conducts literature searches to assist in establishing new laboratory techniques.

Laboratory

  • Accomplishes day-to-day care and housekeeping of laboratory.
  • Assesses the need for and orders all supplies and reagents needed for experiments.
  • Assists in the maintenance of laboratory equipment and safety records, and in the preparation of routine reagents.
  • Monitors laboratory equipment and instrument performance; obtains maintenance and repair as necessary.
  • Maintains computerized records associated with laboratory activities.
  • Instructs others in laboratory methods, procedures, and techniques and provides technical guidance and direction as required.

Miscellaneous

  • May assist in the maintenance of transgenic mouse colonies including weighing of animals, setting up pairs of animals for mating, and entering data into computerized data bases;
  • May assist in surgical procedures.
  • Communicates respectfully with a diverse community.

Research Assistant II
Research/Experiments

  • Independently sets up and monitors experiments in progress.
  • Identifies, troubleshoots, and corrects or recommends solutions to problems associated with experimental design; methods, procedures, and techniques; or equipment and facilities.
  • As necessary, develops and/or implements new or modified research methods, procedures, and techniques to meet the unique requirements of assigned research problems.
  • Adheres to laboratory safety requirements including general and chemical/hazardous waste safety disposal methods.

Data Collection/Preparation

  • Collects, analyzes, and interprets data resulting from experimentation.
  • Performs literature searches to develop information of relevance to the research.
  • Prepares appropriate and understandable representations of data such as sequences, graphs, charts, etc.
  • Participates in the preparation of reports and presentation of the research findings.

Laboratory

  • Schedules and monitors utilization of laboratory facilities, equipment, and supplies.
  • Monitors equipment and instrument performance; obtains necessary maintenance and repair.
  • Orders and maintains stock of laboratory supplies.
  • May provide technical direction to laboratory technicians and student workers.
  • Monitors work in progress to ensure accomplishment is timely and in accordance with reasonable methods and standards.
  • Instructs other in laboratory methods, procedures, and techniques and provides technical guidance and direction as required.

Miscellaneous

  • May assist in the maintenance of transgenic mouse colonies including weighing of animals, setting up pairs of animals for mating, and entering data into computerized data bases.
  • May assist in surgical procedures.
  • Communicates respectfully with a diverse community.
-- Performs other duties as assigned.

Applicant Documents

Required Documents
  1. Resume
  2. Cover Letter
Optional Documents
  1. Additional Document #1
  2. Additional Document #2

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